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Table 1 The differences in urinary NGAL and MMP-9 concentrations and various other parameters among the different groups

From: Identification of urine neutrophil gelatinase-associated lipocalin molecular forms and their association with different urinary diseases in cats

Parameter

Control

 

Non-RP

 

CKD

 

AKI

 

Pyuria

 

A + P

 

p

uNGAL (ng/ml)

0.46 (0.3–0.6) a

n = 12

0.75 (0.5–0.9) b

n = 26

0.37 (0.2–0.6) a

n = 52

1.78 (0.8–6.6) c

n = 21

1.21 (0.5–28.2) b, c

n = 16

11.56 (1.1–47.5) c

n = 27

< 0.001

UNCR (10− 6)

0.17 (0.1–0.3) a

n = 12

0.37 (0.2–1.3) b

n = 26

0.56 (0.2–1.3) b

n = 52

2.92 (1.1–7.7) c, d

n = 21

1.43 (0.4–26.2) c

n = 16

5.50 (1.4–84.7) d

n = 27

< 0.001

Age (years)

5.0 (3–6.8) a

n = 12

7.5 (3.3–12.5) a

n = 24

10.5 (7–15) b

n = 52

11 (9–15) b

n = 22

9.0 (4–11.8) a

n = 16

8 (5.5–13.5) a

n = 27

< 0.001

HCT (%)

40.9 (39–44.7) a

n = 12

30.6 (27.5–36.1) b

n = 23

31 (23–35.8) b

n = 50

27.3 (22.2–33) b

n = 21

30.5 (25.5–36) b

n = 15

31 (24.6–38) b

n = 28

< 0.001

BUN()

7.5 (7–8.8) a

n = 12

7.1 (6.4–8.9) a

n = 25

15.71 (10.7–23.4) b

n = 55

54.4 (33.8–77.7) d

n = 22

6.8 (4.9–8.3) a

n = 15

20.2 (14.3–38.3) c

n = 28

< 0.001

Cre (umol/L)

132 (123–132.6) b

n = 12

110.5 (88.4–123.8) a

n = 26

274.04 (221–406.7) c

n = 55

1127.1 (495.2–1299.7) e

n = 22

92.82 (70.4–123.8 a

n = 16

393.38 (238.7–583.6) d

n = 28

< 0.001

Phos (mmol/L)

–

–

1.45 (1.2–1.7) a, b

n = 14

1.58 (1.3–2) b

n = 49

3.68 (1.7–5.8) c

n = 21

1.36 (0.81–1.49) a

n = 9

2.2 (1.4–3.9) c

n = 26

< 0.001

urine pH

6.4 (6–6.7) c, d

n = 12

6.3 (6–6.6) c, d

n = 26

6 (5.5–6.3)b, c

n = 55

5.6 (5.3–5.9) a

n = 22

6.5 (6.2–7) d

n = 16

6.1 (5.7–6.3) c

n = 28

< 0.001

uRBC (/HPF)

0 (0–2) a

n = 12

0 (0–12.5) a

n = 26

0 (0–9) a

n = 55

2.5 (0–9) a

n = 22

55.5 (20.3–60) b

n = 16

60 (18–60) b

n = 28

< 0.001

uWBC (/HPF)

0 (0–0) a

n = 12

0 (0–0) a

n = 26

0 (0–1) a

n = 55

1 (0–3.3) b

n = 22

24 (9.5–53) c

n = 16

60 (18.5–60) d

n = 28

< 0.001

  1. CKD Chronic kidney disease, AKI Acute kidney injury, Pyuria Pyuria without azotemia, A + P Azotemia with pyuria, Non-RP Diseases without any relation of azotemia and pyuria, NGAL Urinary NGAL, UNCR Urinary NGAL-to-creatinine ratio, HCT Hematocrit, Cre Creatinine, Phos Phosphate, USG Urine specific gravity, uRBC Urine RBC, uWBC Urine WBC, HPF High power field
  2. Data are medians (IQR) and compared by the Kruskal-Wallis test (p < 0.05 indicates significant difference); Dunn’s test for the post hoc test and the different superscripts, a, b, c, d indicate various significant differences
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BMC Veterinary Research

ISSN: 1746-6148

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