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Fig. 1 | BMC Veterinary Research

Fig. 1

From: Effect of female sex hormones on the developmental cycle of Chlamydia abortus compared to a penicillin-induced model of persistent infection

Fig. 1

Transmission electron micrographs of C. abortus inclusions in LE (pictures in left column) and AH-1 cells (right column) at 72 h pi without treatment (a, b) or under estradiol (c, d), progesterone (e, f) or penicillin (g, h) treatment. a Untreated LE cell, normal inclusion containing numerous RBs and few IBs. b Untreated AH-1 cell showing a conventional large inclusion with RBs, IBs and EBs. c Pre-incubation with estradiol induced the presence of several pleomorphic enlarged RBs of different sizes and empty vesicle membranes within the inclusion in LE cells. d AH-1 cell treated with estradiol showing a typical mature inclusion with predominance of EBs and IBs over RBs. e Progesterone treated LE cell containing an inclusion with 2–4 abnormally enlarged atypical AB forms. f Progesterone supplemented AH-1 cell, large inclusion containing many RBs, IBs and EBs with normal shape and morphology. g, h Penicillin treated cultures showing characteristics consistent with a persistent chlamydial infection, both cell lines presented small inclusions with 2–4 giant ABs exclusively

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