The humoral immune response is essential for successful vaccine protection against paratuberculosis in sheep

BMC Veterinary Research

Table 5 Gene expression changes (fold change) in the ileum of sheep to answer specific research questions

		Vaccinated infected compared to vaccinated uninfected (Q3)	Vaccinated infected compared to non-vaccinated infected (Q4)
Up regulated	LYN	1.12	1.36
	GRB2	1.64	1.69
	ERG1		2.17
	JUN	1.14
	NFIL3	2.03	1.28
	LCK
	CD81	1.37
	CD84	2.07
	CD40LG	5.37
	BAFF	2.22
	MIF	2.29
Down regulated	LYN
	GRB2
	ERG1	−1.27
	JUN		−1.36
	NFIL3
	LCK	−1.03	−3.37
	CD81		−2.17
	CD84		−4.31
	CD40LG		−1.68
	BAFF		−7.52
	MIF		−1.82

ISSN: 1746-6148