Skip to main content

Table 2 Analysis matrix for sheep B cell-related gene expression in intestinal tissue for specific research questions

From: The humoral immune response is essential for successful vaccine protection against paratuberculosis in sheep

Research question Baseline group Comparison group (s)
Q1. What gene expression changes are associated with disease outcome in non-vaccinated animals? Are these similar in vaccinated animals? Non-vaccinated control Non-vaccinated infected
Non-vaccinated uninfected
Vaccinated infected
Vaccinated uninfected
Q2. What gene expression changes are associated with disease outcome in vaccinated animals Vaccinated control Vaccinated infected
Vaccinated uninfected
Q3. What gene expression changes are associated with infection in vaccinated animals Vaccinated uninfected Vaccinated infected
Q4. What gene expression changes are associated with vaccination nonresponse in infected animals Non-vaccinated infected Vaccinated infected