Fig. 3

MAP specific-IgG1 serum antibody levels in vaccinated sheep prior to MAP exposure. MAP-specific serum IgG1 levels in vaccinated unexposed sheep (black lines, numbers are individual sheep identifiers) were examined at pre-vaccination and pre-exposure (4 weeks post-vaccination, 2 weeks prior to MAP exposure) time points. The group average values for the vaccinated exposed sheep, categorised as vaccinated infected (tissue culture positive) (n = 2) and vaccinated uninfected (tissue culture negative) (n = 18) are also shown (dashed grey lines)