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Fig. 3 | BMC Veterinary Research

Fig. 3

From: Safety and efficacy of reduced dosage ketoprofen with or without tramadol for long-term treatment of osteoarthritis in dogs: a randomized clinical trial

Fig. 3

Glomerular filtration rate (mL/min/m2) of healthy dogs (group A) and those with osteoarthritis (groups B and C). Evaluations were performed at baseline (D0) and after 7 and 28 days of treatment with standard dosage ketoprofen (Group A, n = 5), or reduced dosage ketoprofen alone (Group B, n = 10) or with tramadol (Group C, n = 10). Data are presented as mean. Error bars represent standard deviation. *Indicates significant within-time difference when compared with baseline (day 0). Different letters indicate statistically significant differences between groups

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