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Table 1 Reproduction parameters achieved with enrofloxacin- and marbofloxacin-treated eggs. Reproduction parameters measured include: Egg numbers set = total eggs of the group incubated, Fertility = percentage of fertilised eggs, Hatchability = percentage of chicks hatching from the fertilised eggs, Pre-term hatching = percentage of chicks hatching on days 19 and 20, Hatching chicks with joint deformity = percentage of chicks showing signs of swollen joints, Total hatching success = percentage of chicks hatching from total eggs set into the incubator. Groups: C1 = untreated control, C2 = sham-treated control eggs (aqua pro injectione); E1, E2, E3 = groups exposed to 1, 10 and 100 μg of enrofloxacin per 1 g of egg weight, respectively; M1, M2, M3 = groups exposed to 1, 10 and 100 μg of marbofloxacin per 1 g of egg weight, respectively; * = p < 0.05, ** = p < 0.01 (compared against control group C1 or C2)

From: Reproductive toxicity of fluoroquinolones in birds

Groups / Parameters

Untreated control

Sham-treated control

Enrofloxacin-treated Dose

Marbofloxacin-treated Dose

C1

C2

Low E1

Medium E2

High E3

Low M1

Medium M2

High M3

Egg numbers set

26

26

20

20

20

20

20

20

Fertility (%)

84

96

90

95

85

95

100

100

Hatchability (%)

90.1

84

55.6

C1*C2*

84.2

35.3

C1**C2**

68.4

65

C1*

45

C1**C2**

Pre-term hatching (%)

0

0

70

C1**C2**

31.3

C1**C2**

33.3

C1**C2**

61.5

C1**C2**

69.2 C1**C2**

44.4

C1**C2**

Hatching chicks with joint deformity (%)

0

0

40

C1**C2**

0

66.67

C1**C2**

15.38

C1*C2*

0

55.56

C1**C2**

Total hatching success (%)

76.9

80.8

50

C2*

80

30

C1**C2**

40

C1*C2**

65

45

C1*C2*