Fig. 2From: Mycobacterium tuberculosis extracellular vesicle-associated lipoprotein LpqH as a potential biomarker to distinguish paratuberculosis infection or vaccination from tuberculosis infectionImmunogenicity of EVs from different mycobacterial strains. Isolated EVs from M. bovis (a), MAP (b) and Mtb H37Rv (c) were separated by SDS-PAGE and submitted to immunoblot with sera from two different cows grouped according to the following treatments: (1) (PTB- TB-), naïve cows; (2) (PTB+) Paratuberculosis positive; (3) (TB+) Bovine tuberculosis positive and; (4) (PTB- Vacc) PTB- and MAP vaccinated cows. d Mtb EVs were also submitted to immunoblot against Mtb EVs-specific serum. The asterisk indicates the presence of the 19 kDa antigenBack to article page