Table 5 Faecal egg count reduction (95% confidence intervals), and EC50 (95% confidence intervals) in the egg hatch test, with goats naturally infected with gastrointestinal nematodes at Nyala (Domaia and Majok), Beleil and Kass, South Darfur State, Sudan, and treated with 5 or 10 mg/kg body weight albendazole
Study area | Season | GI nematodes | Dose and No. of animals in each trial | Day 8 | Day 14 | EC50 (μg thiabendazole /ml) | ||
|---|---|---|---|---|---|---|---|---|
FECR (%) unpaireda | FECR (%) paireda | FECR (%) unpaireda | FECR (%) paireda | |||||
Nyala, Domaia | Autumn | Strongyles | 5 mg/kg Control: n = 30, treated: n = 53 | 75 (61–83) | 72 (71–73) | 72 (61–79) | 69 (68–70) |  |
5 mg/kg Control: n = 10, retreatedb: n = 25 | 62 (22–80) | 34 (29–37) | 48 (11–72) | 18 (13–22) | 0.24 (0.04–1.52) | |||
10 mg/kg Control: n = 10, treated: n = 17 | 90 (84–94) | 92 (91–93) | 80 (53–90) | 84 (83–85) |  | |||
Winter | Strongyles | 10 mg/kg Control: n = 6, treated: n = 8 | 85 (64–93) | 87 (84–89) | 75 (48–89) | 83 (80–86) | 0.18 (0.14–0.24) | |
Nyala, Majok | Winter | Strongyles | 10 mg/kg Treated: n = 10 | n.a.c | 94 (92–95) | n.a.c | 86 (84–88) | 0.18 (0.04–0.81) |
Beleil | Autumn | Strongyles | 5 mg/kg Control: n = 10, treated: n = 30 | 95 (92–97) | 96 (95–96) | 95 (93–97) | 95 (94–95) | 0.06 (0.02–0.17) |
Strongyloides papillosus | 5 mg/kg Treated: n = 3 | n.a.c | 100 | n.a.c | 100 |  | ||
Kass | Autumn | Strongyles | 5 mg/kg Control: n = 15, treated: n = 21 | 89 (82–94) | 92 (91–92) | 77 (63–85) | 74 (73–75) | 0.12 (0.02–0.69) |
Strongyloides papillosus | 5 mg/kg Control: n = 4, treated: n = 4 | 100 | 100 | 100 | 100 |  | ||
Strongyles | 10 mg/kg Control: n = 15, treated: n = 15 | 91 (83–95) | 94 (94–95) | 87 (77–91) | 87 (86–88) | |||