Fig. 7
Acute full-thickness skin wound model. Six mini-pigs were used in this study, and two mini-pigs were paired for creation of two 3 × 3 cm2 full-thickness wound defects (6 cm apart from each other) on the right dorsolateral area of the trunk of each mini-pig. As indicated, hydrocolloid dressing (H), PRP injection (PRP), PRF, or platelet patch (PP), was then applied to the wounds. After application, wound sizes were recorded on days 3, 6, 9, 12 and 14. Subsequently, histological examination was performed at the end of the study. Animal experiments were conducted in triplicate for this study