Fig. 3

Histopathological evaluation of wound healing. a Histological assessment of wounds. The histological parameters of inflammation, epidermis cell debris, angiogenesis, granulation and re-epithelialization are scored from 1 to 5 according to previous report by Altavilla et al. [46] Values are presented as the mean ± standard deviation. Statistical analysis was performed using Student’s two-tailed t-test. There was a significant difference in re-epithelialization scores between the PP (P < 0.05) and PRF and PRP groups. b Representative H&E staining images of wound tissue sections. Ed, epidermal cell debris; In, inflammation; Gn, granulation tissues; Re, re-epithelialization. Scale bar, 200 μm