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Fig. 1 | BMC Veterinary Research

Fig. 1

From: Spontaneous virus reactivation in cattle chronically infected with bovine leukemia virus

Fig. 1

Spontaneous virus reactivation during chronic BLV infection in cattle. The BLV proviral load (black), BLV pol RNA expression (red), level of BLV-sp antibodies (blue dotted line) and the absolute counts of lymphocytes (blue solid line) were followed-up in a single Holstein cow chronically infected with BLV. BLV DNA and RNA levels are expressed as Log10 of copies per μg of total DNA and per ml of plasma, respectively (left axis). BLV-sp Abs were measured by ELISA and are expressed as percent of reactivity (right axis). The dotted horizontal black line represent the limit of detection of BLV qPCR (100 copies per μg). The Figure Insets correspond to a pilot study to assess the effect of a stressor stimuli on BLV infection in cattle. The BLV proviral load (Upper inset) and BLV pol RNA expression (Lower inset) were followed-up in four cattle infected with BLV; three of these cattle received DEX treatment (IDs# 177, 190 and 230) and one was used as an untreated control (Animal 184). All these parameters were measured in peripheral blood. BLV DNA and RNA levels are expressed as Log10 of copies per μg of total DNA and per ml of plasma. The dotted horizontal black line represent the limit of detection of BLV qPCR (100 copies per μg). Black arrows represent DEX administrations

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