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Table 2 Hematology mean values observed in cats treated with oral oclacitinib or placebo

From: A blinded, randomized, placebo-controlled trial of the safety of oclacitinib in cats

Parameter Placebo 1 mg/kg 2 mg/kg
Day −2 Day 7 Day 14 Day 28 Day 42 Day −2 Day 7 Day 14 Day 28 Day 42 Day −2 Day 7 Day 14 Day 28 Day 42
RBC (× 106 /μL) 9.53 9.05 9.71 9.34 9.75 9.06 8.62 9.19 9.16 9.25 9.39 9.69 9.39 9.02 9.63
Hemoglobin (g/dL) 11.81 11.64 12.55 11.66 12.10 12.18 11.78 12.27 11.66 11.94 12.38 12.75 11.97 11.60 12.40
Hematocrit (%) 39.13 36.35 40.49 38.76 39.11 38.97 37.54 39.03 39.63 38.10 40.00 39.38 40.00 38.12 39.67
WBC (/μL) 10,887 12,564 12,640 12,620 12,090 12,410 15,760 14,910 14,970 14,070 11,160 13,430 13,330 11,460 11,010
Neutrophils 6232.5 7590 5608.6 6983.7 6390.0 7662.3 8595.5 8877.4 7804.9 9168.9 6071.6 7179.4 6823.5 5635.7 6235.8
Lymphocytes 3556.8 4615.1 5049.0 4619.1 4609.6 3546.6 5924.3 4830.4 4968.5 3737.4 3753.0 6094.1 5334.6 5002.4 3468.3
Monocytes 208.6 301.0 448.2 329.7 237.0 205.8 280.2 293.3 361.6 353.2 199.4 287.1 222.5 209.4 261.7
Eosinophils 695.2 825.70 850.2 1040.5 831.2 1257.3 960.0 908.9a 962.4 810.5 1136.2 689.4 470.1a 612.5 1033.3
Platelets (/μL) 161,900 186,100 165,600 170,100 124,200 162,900 170,000 162,900 161,200 128,500 181,300 190,800 155,300 265,700 162,200
  1. RBC red blood cells, WBC white blood cells
  2. aSignificantly different than placebo value at the same day (p = 0.04)
  3. Reference values: RBC-6.0-10.0; hemoglobin- 9.5-15.0; hematocrit- 29-45; WBC- 5.5-19.5 × 103; neutrophils-2500-12,500; lymphocytes- 1500-7000; monocytes- 0-850; eosinophils-0-1500; platelets- 150-600 × 103