Table 2 Hematology mean values observed in cats treated with oral oclacitinib or placebo
From: A blinded, randomized, placebo-controlled trial of the safety of oclacitinib in cats
Parameter | Placebo | 1 mg/kg | 2 mg/kg | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Day −2 | Day 7 | Day 14 | Day 28 | Day 42 | Day −2 | Day 7 | Day 14 | Day 28 | Day 42 | Day −2 | Day 7 | Day 14 | Day 28 | Day 42 | |
RBC (× 106 /μL) | 9.53 | 9.05 | 9.71 | 9.34 | 9.75 | 9.06 | 8.62 | 9.19 | 9.16 | 9.25 | 9.39 | 9.69 | 9.39 | 9.02 | 9.63 |
Hemoglobin (g/dL) | 11.81 | 11.64 | 12.55 | 11.66 | 12.10 | 12.18 | 11.78 | 12.27 | 11.66 | 11.94 | 12.38 | 12.75 | 11.97 | 11.60 | 12.40 |
Hematocrit (%) | 39.13 | 36.35 | 40.49 | 38.76 | 39.11 | 38.97 | 37.54 | 39.03 | 39.63 | 38.10 | 40.00 | 39.38 | 40.00 | 38.12 | 39.67 |
WBC (/μL) | 10,887 | 12,564 | 12,640 | 12,620 | 12,090 | 12,410 | 15,760 | 14,910 | 14,970 | 14,070 | 11,160 | 13,430 | 13,330 | 11,460 | 11,010 |
Neutrophils | 6232.5 | 7590 | 5608.6 | 6983.7 | 6390.0 | 7662.3 | 8595.5 | 8877.4 | 7804.9 | 9168.9 | 6071.6 | 7179.4 | 6823.5 | 5635.7 | 6235.8 |
Lymphocytes | 3556.8 | 4615.1 | 5049.0 | 4619.1 | 4609.6 | 3546.6 | 5924.3 | 4830.4 | 4968.5 | 3737.4 | 3753.0 | 6094.1 | 5334.6 | 5002.4 | 3468.3 |
Monocytes | 208.6 | 301.0 | 448.2 | 329.7 | 237.0 | 205.8 | 280.2 | 293.3 | 361.6 | 353.2 | 199.4 | 287.1 | 222.5 | 209.4 | 261.7 |
Eosinophils | 695.2 | 825.70 | 850.2 | 1040.5 | 831.2 | 1257.3 | 960.0 | 908.9a | 962.4 | 810.5 | 1136.2 | 689.4 | 470.1a | 612.5 | 1033.3 |
Platelets (/μL) | 161,900 | 186,100 | 165,600 | 170,100 | 124,200 | 162,900 | 170,000 | 162,900 | 161,200 | 128,500 | 181,300 | 190,800 | 155,300 | 265,700 | 162,200 |