Fig. 1

Timeline of calf vaccinations and sample collection. For vaccine details see Methods section. Of note, at no time during the study were calves vaccinated with a BCV containing vaccine. Mass treatment for BRD occurred in a subset of claves from Herd 2 on August 5, 2016 (mass treatment 1, MT-1; n = 93 study calves) and August 12, 2016 (mass treatment 2, MT-2; n = 142 study calves). Additional details are in the Methods