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Table 1 The inhibitory effect of LPS on dermal cells(n = 8)

From: Effects of silymarin on p65 NF-κB, p38 MAPK and CYP450 in LPS-induced hoof dermal inflammatory cells of dairy cows

LPS (μg/mL)

Absorbance value

IR(%)

0

0.865 ± 0.074

0

1

0.842 ± 0.050

2.61

5

0.803 ± 0.052

7.10

10

0.772 ± 0.050*

10.73

20

0.702 ± 0.025**

18.80

50

0.622 ± 0.036**

28.08

  1. Note: Cells were treated with gradient concentrations of LPS for 48 h, and the viability was monitored by MTT assay. Value indicated are the mean ± SD (**P-value< 0.01; *P-value< 0.05). The inhibition ratio (IR) = 1- (the test group OD value/ the control group OD value)