Fig. 4

CYP3A4 and CYP1A1 expressions measured with qRT-PCR. With LPS treatment for 24 h and 48 h in hoof dermal cells, the expressions of CYP3A4 (a) and CYP1A1 (b) were detected (n = 8). (^**P-value< 0.01; ^*P-value< 0.05, compared with the control group). After treated with silymarin for 24 h and 48 h in LPS-induced inflammatory cells, the expressions of CYP3A4 (c) and CYP1A1 (d) were detected (n = 8). (^**P-value< 0.01; ^*P-value< 0.05, compared with the LPS model group)