TY - JOUR AU - Ceric, Olgica AU - Tyson, Gregory H. AU - Goodman, Laura B. AU - Mitchell, Patrick K. AU - Zhang, Yan AU - Prarat, Melanie AU - Cui, Jing AU - Peak, Laura AU - Scaria, Joy AU - Antony, Linto AU - Thomas, Milton AU - Nemser, Sarah M. AU - Anderson, Renee AU - Thachil, Anil J. AU - Franklin-Guild, Rebecca J. AU - Slavic, Durda AU - Bommineni, Yugendar R. AU - Mohan, Shipra AU - Sanchez, Susan AU - Wilkes, Rebecca AU - Sahin, Orhan AU - Hendrix, G. Kenitra AU - Lubbers, Brian AU - Reed, Deborah AU - Jenkins, Tracie AU - Roy, Alma AU - Paulsen, Daniel AU - Mani, Rinosh AU - Olsen, Karen AU - Pace, Lanny AU - Pulido, Martha AU - Jacob, Megan AU - Webb, Brett T. AU - Dasgupta, Sarmila AU - Patil, Amar AU - Ramachandran, Akhilesh AU - Tewari, Deepanker AU - Thirumalapura, Nagaraja AU - Kelly, Donna J. AU - Rankin, Shelley C. AU - Lawhon, Sara D. AU - Wu, Jing AU - Burbick, Claire R. AU - Reimschuessel, Renate PY - 2019 DA - 2019/05/06 TI - Enhancing the one health initiative by using whole genome sequencing to monitor antimicrobial resistance of animal pathogens: Vet-LIRN collaborative project with veterinary diagnostic laboratories in United States and Canada JO - BMC Veterinary Research SP - 130 VL - 15 IS - 1 AB - Antimicrobial resistance (AMR) of bacterial pathogens is an emerging public health threat. This threat extends to pets as it also compromises our ability to treat their infections. Surveillance programs in the United States have traditionally focused on collecting data from food animals, foods, and people. The Veterinary Laboratory Investigation and Response Network (Vet-LIRN), a national network of 45 veterinary diagnostic laboratories, tested the antimicrobial susceptibility of clinically relevant bacterial isolates from animals, with companion animal species represented for the first time in a monitoring program. During 2017, we systematically collected and tested 1968 isolates. To identify genetic determinants associated with AMR and the potential genetic relatedness of animal and human strains, whole genome sequencing (WGS) was performed on 192 isolates: 69 Salmonella enterica (all animal sources), 63 Escherichia coli (dogs), and 60 Staphylococcus pseudintermedius (dogs). SN - 1746-6148 UR - https://doi.org/10.1186/s12917-019-1864-2 DO - 10.1186/s12917-019-1864-2 ID - Ceric2019 ER -