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Table 1 Number and frequency (%) with 95% CIa of individual worm genotypes with “susceptible” and “resistant” single nucleotide polymorphism (SNP) and the allele frequency (%) with 95% CI at codon E198A (GAA/GCA) associated with benzimidazole resistance in isotype-1 β-tubulin gene of H. contortus worms from sympatric blue sheep and sheep in Helan Mountains, China

From: A detection of benzimidazole resistance-associated SNPs in the isotype-1 β-tubulin gene in Haemonchus contortus from wild blue sheep (Pseudois nayaur) sympatric with sheep in Helan Mountains, China

Hosts Number of genotypeb and frequency (%) with 95% CI Frequencyc (%) with 95% CI for codon E198A
Hs-198 Hr-198 Het-198 Susceptible Resistant
Sheep 17 (85.00, 63.96~94.76) 0 (0.00, 0.00~16.11) 3 (15.00, 5.24~36.04) (92.50, 80.14~97.42) (7.50, 2.58~19.86)
Blue sheep 23 (85.20, 67.52~94.08) 2 (7.40, 2.06~23.37) 2 (7.40, 2.06~23.37) (88.89, 77.81~94.81) (11.11, 5.19~22.19)
  1. a CI Confidence interval
  2. b Genotype: Hs, homozygous susceptible; Hr, homozygous resistant; Het, heterozygote
  3. c The allele frequency for codon E198A (%) was calculated using as below: Susceptible of sheep = (Hs-198× 2 + Het-198)/(20 × 2). Resistant of sheep = (Hr-198× 2 + Het-198)/(20 × 2). Susceptible of blue sheep = (Hs-198× 2 + Het-198)/(27 × 2). Resistant of blue sheep = (Hr-198× 2 + Het-198)/(27 × 2)