TY - JOUR AU - Vansteenkiste, Daniella AU - Martin-Vaquero, Paula AU - Bonelli, MarĂ­lia AU - da Costa, Luciana B. AU - da Costa, Ronaldo C. PY - 2019 DA - 2019/03/12 TI - Long-term computed tomography follow-up in great Danes with or without signs of osseous- associated cervical Spondylomyelopathy JO - BMC Veterinary Research SP - 90 VL - 15 IS - 1 AB - Osseous- associated cervical spondylomyelopathy (OA-CSM) has a high prevalence in Great Danes. In order to understand the progression of osseous changes, we aimed to perform a long-term computed tomographic (CT) follow-up study of Great Dane dogs with and without OA-CSM. Canine CSM is comparable to a common neurologic disease often diagnosed in older people termed cervical spondylotic myelopathy or degenerative cervical myelopathy, which is progressive in nature. The natural history of cervical spondylotic myelopathy in people has been well described, whereas there is scarce information on the natural history of canine OA-CSM. Our first goal was to evaluate if follow-up CT studies showed any changes compared to initial CT studies in Great Dane dogs with a diagnosis of OA-CSM. Our second goal was to establish whether clinically normal Great Danes went on to develop any vertebral changes or clinical signs consistent with OA-CSM. We enrolled Great Danes diagnosed with OA-CSM and clinically normal Great Danes who had previously participated in a prospective study. All dogs had clinical and CT follow-up evaluations. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-019-1835-7 DO - 10.1186/s12917-019-1835-7 ID - Vansteenkiste2019 ER -