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Fig. 1 | BMC Veterinary Research

Fig. 1

From: Coordinated expression of vascular endothelial growth factor A and urokinase-type plasminogen activator contributes to classical swine fever virus Shimen infection in macrophages

Fig. 1

The role of VEGFA and PLAU in the co-expression network of cells infected by CSFV Shimen. (a) The co-expression network shows that VEGFA and PLAU are up-regulated in CSFV Shimen-infected cells compared to their levels in CSFV C-infected and mock-infected cells. (b) protein–protein interaction analysis of VEGFA. Each network node represents all proteins produced by a single protein-coding gene locus, and the edges represent protein-protein associations, which means proteins together contribute to shared functions. The meaning of the network edge is confidence, and the thickness of the line indicates the strength of data supports, which edge confidence is divided into 3 levels: medium (0.400), high (0.700), and highest (0.900). (c) GO analysis shows that aberrant expression of VEGFA is related to anomalous regulation of gene function groups

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