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Table 3 Stepwise multivariate Cox regression analysis

From: Prognostic significance of circulating microRNA-214 and -126 in dogs with appendicular osteosarcoma receiving amputation and chemotherapy

 

Long-term DFS

1-year DFS

Long-term OS

1-year OS

P-value

HR

95%CI

P-value

HR

95%CI

P-value

HR

95%CI

P-value

HR

95%CI

miR-214 High

(ACRQ, 0.92<)

0.0004 ***

3.51

1.68–8.55

0.001 ***

4.24

1.69–14.21

0.005 **

2.95

1.35–7.77

0.013 *

3.17

1.25–10.71

miR-126 Low

(ACRQ, < 1.4)

–

–

–

0.003 **

8.09

1.75–143.59

–

–

–

–

–

–

ALP High

(U/L, 96<)

–

–

–

–

–

–

0.007 **

2.26

1.26–4.06

0.0047 **

2.6

1.34–5.15

Model fitness

0.0004 ***

–

–

< 0.0001 ***

–

–

0.0002 ***

–

–

0.0003 ***

–

–

  1. Stepwise multivariate Cox regression analysis identified independent variables for the prediction of the DFS and OS. P-values less than 0.05 were considered to be significant (*P < 0.05, **P < 0.01, ***P < 0.001). HR, hazard ratio; 95% CI, 95% confidential interval