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Table 4 Prognostic value of Bcl-2 expression estimated by multivariate analysis in 57 luminal FMCs

From: Bcl-2 expression and prognostic significance in feline invasive mammary carcinomas: a retrospective observational study

 

Categories

p

HR

95%-CI

Disease-free interval

 Bcl-2 expression

Bcl-2+ versus Bcl-2–

0.017

0.09

0.01–0.64

 Pathologic tumor size

pT ≥ 20 mm versus < 20 mm

0.047

2.23

1.02–4.91

 Tumor-associated inflammation

Absence to mild versus moderate to severe

0.033

0.40

0.18–0.92

Overall survival

 Bcl-2 expression

Bcl-2+ versus Bcl-2–

0.008

0.28

0.11–0.72

 Pathologic tumor size

pT ≥ 20 mm versus < 20 mm

0.014

2.07

1.16–3.70

 Tumor-associated inflammation

Absence to mild versus moderate to severe

0.012

0.44

0.23–0.84

Cancer-specific survival

 Bcl-2 expression

Bcl-2+ versus Bcl-2–

0.031

0.31

0.11–0.89

 Pathologic tumor size

pT ≥ 20 mm versus < 20 mm

0.026

2.10

1.09–4.02

 Tumor-associated inflammation

Absence to mild versus moderate to severe

0.022

0.43

0.21–0.88