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Table 4 Prognostic value of Bcl-2 expression estimated by multivariate analysis in 57 luminal FMCs

From: Bcl-2 expression and prognostic significance in feline invasive mammary carcinomas: a retrospective observational study

  Categories p HR 95%-CI
Disease-free interval
 Bcl-2 expression Bcl-2+ versus Bcl-2– 0.017 0.09 0.01–0.64
 Pathologic tumor size pT ≥ 20 mm versus < 20 mm 0.047 2.23 1.02–4.91
 Tumor-associated inflammation Absence to mild versus moderate to severe 0.033 0.40 0.18–0.92
Overall survival
 Bcl-2 expression Bcl-2+ versus Bcl-2– 0.008 0.28 0.11–0.72
 Pathologic tumor size pT ≥ 20 mm versus < 20 mm 0.014 2.07 1.16–3.70
 Tumor-associated inflammation Absence to mild versus moderate to severe 0.012 0.44 0.23–0.84
Cancer-specific survival
 Bcl-2 expression Bcl-2+ versus Bcl-2– 0.031 0.31 0.11–0.89
 Pathologic tumor size pT ≥ 20 mm versus < 20 mm 0.026 2.10 1.09–4.02
 Tumor-associated inflammation Absence to mild versus moderate to severe 0.022 0.43 0.21–0.88