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Table 4 Different KEGG entries between Diarrheal piglets and Control piglets

From: Intestinal microbiota mediates Enterotoxigenic Escherichia coli-induced diarrhea in piglets

Levels Fold change (Diarrhea/Control) Annotation
KEGG level 1
  0.77 Cellular Processes
KEGG level 2
  0.71 Cell Motility
  0.77 Biosynthesis of Other Secondary Metabolites
  1.28 Excretory System
  1.29 Immune System Diseases
  1.58 Immune System
  2.89 Circulatory System
KEGG level 3
  0.31 N-Glycan biosynthesis
  0.34 Flavone and flavonol biosynthesis
  0.35 Bacterial invasion of epithelial cells
  0.40 Penicillin and cephalosporin biosynthesis
  0.42 beta-Lactam resistance
  0.43 Stilbenoid, diarylheptanoid and gingerol biosynthesis
  0.59 Bisphenol degradation
  0.62 Apoptosis
  0.62 Non-homologous end-joining
  0.63 Secretion system
  0.65 Adipocytokine signaling pathway
  0.67 Bacterial motility proteins
  0.68 Other glycan degradation
  0.69 Phenylalanine metabolism
  0.70 Isoquinoline alkaloid biosynthesis
  0.71 Biosynthesis of vancomycin group antibiotics
  0.71 Carbohydrate metabolism
  0.72 Lysosome
  0.73 Tropane, piperidine and pyridine alkaloid biosynthesis
  0.73 beta-Alanine metabolism
  0.73 Glycosaminoglycan degradation
  0.73 Replication, recombination and repair proteins
  0.75 Ethylbenzene degradation
  0.75 Nucleotide metabolism
  0.75 Geraniol degradation
  0.76 Polyketide sugar unit biosynthesis
  0.76 Bladder cancer
  0.77 Ribosome biogenesis in eukaryotes
  0.78 Vibrio cholerae pathogenic cycle
  0.78 Limonene and pinene degradation
  0.78 Dioxin degradation
  0.79 Glyoxylate and dicarboxylate metabolism
  0.79 Flagellar assembly
  0.79 Caprolactam degradation
  0.79 Energy metabolism
  1.21 Aminoacyl-tRNA biosynthesis
  1.21 Zeatin biosynthesis
  1.22 DNA replication
  1.22 Terpenoid backbone biosynthesis
  1.22 Homologous recombination
  1.24 Steroid biosynthesis
  1.24 Carotenoid biosynthesis
  1.24 D-Glutamine and D-glutamate metabolism
  1.24 Peptidoglycan biosynthesis
  1.24 Ribosome
  1.24 Ribosome
  1.24 Mismatch repair
  1.25 Nucleotide excision repair
  1.25 Pyrimidine metabolism
  1.26 Phenylpropanoid biosynthesis
  1.26 Proximal tubule bicarbonate reclamation
  1.26 Phosphotransferase system (PTS)
  1.27 Alzheimer’s disease
  1.28 Primary immunodeficiency
  1.28 MAPK signaling pathway - yeast
  1.29 Lysine biosynthesis
  1.31 Cyanoamino acid metabolism
  1.32 Fatty acid biosynthesis
  1.32 Ubiquitin system
  1.33 Pentose phosphate pathway
  1.34 Photosynthesis proteins
  1.36 Sphingolipid metabolism
  1.36 RNA transport
  1.36 Photosynthesis
  1.40 D-Alanine metabolism
  1.41 Butirosin and neomycin biosynthesis
  1.47 Histidine metabolism
  1.51 Restriction enzyme
  1.59 Glycerolipid metabolism
  1.90 Inositol phosphate metabolism
  2.00 Phosphonate and phosphinate metabolism
  2.01 Glycosphingolipid biosynthesis - globo series
  2.14 Sporulation
  2.23 Steroid hormone biosynthesis
  2.47 Linoleic acid metabolism
  2.86 Cardiac muscle contraction
  2.86 Parkinson’s disease
  4.95 Ether lipid metabolism
  6.59 Glycosphingolipid biosynthesis - ganglio series
  20.58 Staphylococcus aureus infection
  21.64 Primary bile acid biosynthesis
  21.64 Secondary bile acid biosynthesis
  70.47 Atrazine degradation
  1. KEGG entries in the intestinal microbiota of the jejunum among diarrheal piglets, recovered piglets, controls, and resistant piglets were analyzed using metagenomics (n = 3 before pooling). The fold changes of KEGG entries at each levels were calculated based on the relative percentage of KEGG entries in diarrheal piglets to the relative percentage of KEGG entries in control piglets. Those KEGG entries with the values of fold change < 0.8 or > 1.2 are listed