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Fig. 2 | BMC Veterinary Research

Fig. 2

From: Safety and efficacy of aged garlic extract in dogs: upregulation of the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway and Nrf2-regulated phase II antioxidant enzymes

Fig. 2

The effect of aged garlic extract (AGE) on the expression of canine NQO1, GCLM, HMOX1, and SOD2 genes in the whole blood.

Relative mRNA expression levels in whole blood samples from dogs administered AGE at doses of 45 and 90 mg/kg/day at weeks 8 and 12 are shown as fold induction compared with those in water-treated control group (C). The expression level is calculated as the ratio of expression after administration to that before administration of AGE. Data are presented as the mean ± standard deviation of the results from three independent experiments. *p < 0.05 and **p < 0.01 vs control with a statistical significance

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