Table 2 Susceptibility to various tetracycline antibiotics stratified by the presence or absence of class 1 integrons
Antimicrobial agents | Intl1 present | Intl1 Absent | P value | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
MIC (μg/ml) | Number (%) of resistant isolates | MIC (μg/ml) | Number (%) of resistant isolates | ||||||||
Range | MIC50 | MIC90 | Range | MIC50 | MIC90 | ||||||
Tetracycline | 64 | > 256 | 128 | 256 | 38 (41.3) | 16 | > 256 | 128 | 256 | 54 (58.7) | 0.244 |
Doxycycline | 4 | 128 | 16 | 64 | 36 (39.1) | 4 | 64 | 32 | 64 | 44 (47.8) | 0.975 |
Oxytetracycline | 64 | > 256 | > 256 | > 256 | 38 (41.3) | 32 | > 256 | 256 | > 256 | 54 (58.7) | P<0.006 |
Minocycline | 4 | 64 | 8 | 32 | 14 (15.2) | 2 | 64 | 16 | 32 | 28 (30.4) | 0.267 |
Tigecycline | 0.25 | 2 | 1 | 1 | – | 0.25 | 8 | 0.5 | 1 | 1 (1.1) | 0.054 |