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Table 3 Associations between pSmad2, TAZ and YAP levels and established prognostic factors

From: An evaluation of TAZ and YAP crosstalk with TGFβ signalling in canine osteosarcoma suggests involvement of hippo signalling in disease progression

Histopathological Characteristics

pSmad2

p value

TAZ

p value

YAP

p value

High

Low

 

High

Low

 

High

Low

 

Tumour Grade

 Kirpensteijn et al. (2002) [28]

  1

0

0

0.1366

0

0

0.3747

0

0

0.2549

  2

7

6

 

8

5

 

7

5

 

  3

3

0

 

1

2

 

2

0

 

 Loukopoulos et al. (2007) [29]

  

0.0907

  

0.6832

  

0.1629

  1

3

5

 

4

4

 

3

4

 

  2

4

0

 

2

2

 

4

0

 

  3

3

1

 

3

1

 

2

1

 

 Serum ALPa Status

  

0.5510

  

0.1457

  

0.0524

  High

3

1

 

1

3

 

8

2

 

  Normal

7

5

 

8

4

 

1

3

 

  Low

0

0

 

0

0

 

0

0

 
  1. aALP: Alkaline phosphatase