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Table 3 Associations between pSmad2, TAZ and YAP levels and established prognostic factors

From: An evaluation of TAZ and YAP crosstalk with TGFβ signalling in canine osteosarcoma suggests involvement of hippo signalling in disease progression

Histopathological Characteristics pSmad2 p value TAZ p value YAP p value
High Low   High Low   High Low  
Tumour Grade
 Kirpensteijn et al. (2002) [28]
  1 0 0 0.1366 0 0 0.3747 0 0 0.2549
  2 7 6   8 5   7 5  
  3 3 0   1 2   2 0  
 Loukopoulos et al. (2007) [29]    0.0907    0.6832    0.1629
  1 3 5   4 4   3 4  
  2 4 0   2 2   4 0  
  3 3 1   3 1   2 1  
 Serum ALPa Status    0.5510    0.1457    0.0524
  High 3 1   1 3   8 2  
  Normal 7 5   8 4   1 3  
  Low 0 0   0 0   0 0  
  1. aALP: Alkaline phosphatase