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Table 1 Clinical and histopathological characteristics of appendicular OSA cases included in metastasis and survival analyses

From: An evaluation of TAZ and YAP crosstalk with TGFβ signalling in canine osteosarcoma suggests involvement of hippo signalling in disease progression

Case BREED SEX Age Dx (Y) Weight Dx (kg) Location ALP Status Survival Days Metastasis pSmad2 Levels TAZ
Levels
YAP
Levels
Grade
Kirp Louko
1 Standard Poodle CM 10.55 23.6 right proximal tibia N 91 84 High High N/A 3 3
2 Doberman SF 5.99 32.4 right distal femur H 116 93 High High Low 2 3
3 Rottweiler M 6.30 53.0 left proximal humerus H 130 N/A High Low Low 2 1
4 Australian Shepherd CM 8.32 24.6 right proximal humerus N 148 78 High High High 2 2
5 Rottweiler CM 8.26 50.0 right distal radius H 165 131 High Low High 2 2
6 Greyhound SF 8.87 26.0 right distal femur N 215 N/A High Low High 3 2
7 Mixed breed CM 8.30 37.4 left distal radius N 218 167 Low High High 2 1
8 Rottweiler CM 4.66 53.4 left proximal humerus N 282 182 Low High High 2 3
9 Golden Retriever CM 10.99 32.2 left proximal tibia N 294a 247 Low Low High 2 1
10 Mixed breed CM 10.02 42.0 left distal tibia N 301 N/A High High High 2 1
11 Mixed breed CM 7.25 51.0 left distal tibia N 381 N/A High High High 2 2
12 Doberman SF 5.91 41.0 right distal radius N 485a 485a High Low High 3 3
13 Mixed breed CM 8.03 28.4 left proximal femur N 605 604 Low Low Low 2 1
14 Greyhound CM 9.02 29.4 right distal femur N 1005 1005a High High N/A 2 1
15 Mixed breed CM 8.25 37.2 left proximal femur N 1386 1386a Low High Low 2 1
16 Greyhound SF 7.43 32.4 left distal tibia H 1091a 1091a Low Low Low 2 1
  1. MC male castrated, FS female spayed, ALP alkaline phosphatase status, H high, N normal, L low; Kirp, Grade assigned using criteria as explained in Kirpensteijn et al. [28]; Louko, Grade assigned using criteria as explained in Loukopoulos et al. [29];
  2. N/A Data not available
  3. aData was censored for Kaplan-Meier analysis