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Table 1 Upregulated proteins under mimetic conditions related to pathogenesis and located on the bacterial surface

From: Transcriptomics of Haemophilus (Glässerella) parasuis serovar 5 subjected to culture conditions partially mimetic to natural infection for the search of new vaccine antigens

Locus a

GenBank product

Access number Uniprot

Name Uniprot

Pathogenesis

Location

HAPS_RS00370

protein TolA

B8F375

|tolA|Cell envelope integrity inner membrane protein TolA

P

IM

HAPS_RS00485

TonB-dependent receptor

P

OM

HAPS_RS00735

hypothetical protein

P

OM

HAPS_RS00740 a

autotransporter domain-containing protein

P

OMa

HAPS_RS00745 a

hypothetical protein

P

EX

HAPS_RS01255

ABC transporter permease

B8F3P0

|HAPS_0253|ABC-type nitrate/sulfonate/bicarbonate transport permease

P

IM

HAPS_RS01260

ABC transporter substrate-binding protein

B8F3P1

|HAPS_0254|ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components protein

P

CP

HAPS_RS01265

ABC transporter ATP-binding protein

B8F3P2

|HAPS_0255|ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase

P

IM

HAPS_RS01400

sulfurtransferase FdhD

P

CP

HAPS_RS01435

hypothetical protein

B8F3S4

|HAPS_0289|Uncharacterized protein

P

CP

HAPS_RS01805

ABC transporter ATPase

B8F3Z5

|HAPS_0364|ATPase components of ABC transporters with duplicated ATPase domains-containing protein

P

PP

HAPS_RS01895

hypothetical protein

B8F410

|HAPS_0382|Uncharacterized protein

P

EX

HAPS_RS02610

hypothetical protein

B8F4D5

|purL|Phosphoribosylformylglycinamidine synthase

P

CP

HAPS_RS03735

fimbrial usher protein

P

OM

HAPS_RS04480

hypothetical protein

P

PP

HAPS_RS04485

hypothetical protein

B8F5E9

|HAPS_0923|Uncharacterized protein

P

EX

HAPS_RS06520

hypothetical protein

B8F6H3

|yaaH|Permease, Inner membrane protein yaaH

P

IM

HAPS_RS00370

protein TolA

B8F375

|tolA|Cell envelope integrity inner membrane protein TolA

P

IM

HAPS_RS00485

TonB-dependent receptor

P

OM

HAPS_RS00735

hypothetical protein

P

OM

HAPS_RS00740 a

autotransporter domain-containing protein

P

OM

HAPS_RS00745 a

hypothetical protein

P

EX

HAPS_RS06610

cell envelope protein TonB

B8F6J2

|tonB|Protein TonB

P

PP

HAPS_RS07630

iron ABC transporter permease

B8F723

|hmuU|Hemin transport system permease protein HmuU

P

IM

HAPS_RS07950

hypothetical protein

P

CP

HAPS_RS09000

hypothetical protein

B8F7Q0

|HAPS_1850|Uncharacterized protein

P

IM

HAPS_RS10195

DUF262 domain-containing protein

B8F899

|HAPS_2100|Uncharacterized protein

P

CP

HAPS_RS10530

TolC family protein tolC

B8F8F2

|tolC|RND efflux system outer membrane lipoprotein/RND superfamily resistance-nodulation-cell division antiporter

P

OM

HAPS_RS10585

ligand-gated channel

B8F8G2

|hxuC|Heme/hemopexin utilization protein C/outer membrane receptor protein, mostly Fe transport

P

OM

HAPS_RS10590

ShlB/FhaC/HecB family hemolysin secretion/activation protein

B8F8G3

|hxuB|Heme/hemopexin-binding protein B, hemolysin activation/secretion protein

P

OM

HAPS_RS10595

hypothetical protein

B8F8G4

|hxuA|Heme/hemopexin-binding protein A (Heme:hemopexin utilization protein A)

P

EX

HAPS_RS10780

membrane protein

B8F8J9

|HAPS_2219|Possible outer membrane protein/FOG: TPR repeat protein

P

OM

HAPS_RS10800

transferrin-binding protein-like solute binding protein

P

OM

HAPS_RS10805

lactoferrin/transferrin family TonB-dependent receptor

B8F8K4

|tbpA|Transferrin-binding protein 1

P

OM

HAPS_RS11010

transpeptidase

B8F8P5

|HAPS_2267|Uncharacterized protein

P

PP

HAPS_RS11030

transcriptional regulator

B8F8P9

|impA|SOS-response transcriptional repressor

P

CP

  1. P indicates the relationship to pathogenesis; Locations are indicated by: OM outer membrane, EX extracellular, IM inner membrane, PP periplasmic, CP cytoplasmic. The locus in the reference genome (SH0165 strain) is indicated. a indicates that this was a single protein recognized as two different ones.