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Table 2 Breakpoints for antimicrobial susceptibility of Staphylococcus pseudintermedius or Staphylococcus spp. according to Clinical and Laboratory Standards Institute (CLSI VET 01 S3, 2015)

From: Occurrence and characterization of methicillin-resistant Staphylococcus pseudintermedius in successive parturitions of bitches and their puppies in two kennels in Italy

Antimicrobial agent
  S I R  
Oxacillin ≤0.25 ≥0.5 Staphylococcus pseudintermedius dog
Ampicillin ≤0.25 ≥0.5 S.pseudintermedius dog
Penicillin ≤0.5 1 ≥2.0 Staphylococcus spp. (other species: horse)
Amoxicillin/Clavulanic acid ≤0.25/0.12 0.5/0.25 ≥1/0.5 Staphylococcus spp. dog
Cefazolin ≤2 4 ≥8 S.pseudintermedius dog
Cefpodoxime ≤2 4 ≥8 S.pseudintermedius dog
Ceftiofur ≤2 4 ≥8 S. aureus (other species: cattle)
Trimethoprim-sulfamethox. ≤2/38 ≥4/76 Staphylococcus spp. human-derived MIC breakpoints
Amikacin ≤4 8 ≥16 Staphylococcus spp. dog
Rifampicin ≤1 2 ≥4 Staphylococcus spp. human-derived MIC breakpoints
Enrofloxacin ≤0.5 1–2 ≥4 Staphylococcus spp. dog
Marbofloxacin ≤1 2 ≥4 Staphylococcus spp. dog
Clindamycin ≤0.5 1–2 ≥4 Staphylococcus spp. dog
Erythromycin ≤0.5 1–4 ≥8 Staphylococcus spp. human-derived MIC breakpoints
Doxycycline ≤0.12 0.25 ≥0.5 S. pseudintermedius dog
Chloramphenicol ≤8 16 ≥32 Staphylococcus spp. human-derived MIC breakpoints
Gentamicina ≤4 8 ≥16 human-derived MIC breakpoints
Ticarcillinb ≤16 32–64 ≥128 human-derived MIC breakpoints
Ticarcillin/Clavulanic acidb ≤16/2 32/2–64/2 ≥128/2 human-derived MIC breakpoints
  1. a [18] b EUCAST, [19]