Table 2 Breakpoints for antimicrobial susceptibility of Staphylococcus pseudintermedius or Staphylococcus spp. according to Clinical and Laboratory Standards Institute (CLSI VET 01 S3, 2015)

S

I

R

Oxacillin

≤0.25

–

≥0.5

Staphylococcus pseudintermedius dog

Ampicillin

≤0.25

–

≥0.5

S.pseudintermedius dog

Penicillin

≤0.5

1

≥2.0

Staphylococcus spp. (other species: horse)

Amoxicillin/Clavulanic acid

≤0.25/0.12

0.5/0.25

≥1/0.5

Staphylococcus spp. dog

Cefazolin

≤2

4

≥8

S.pseudintermedius dog

Cefpodoxime

≤2

4

≥8

S.pseudintermedius dog

Ceftiofur

≤2

4

≥8

S. aureus (other species: cattle)

Trimethoprim-sulfamethox.

≤2/38

–

≥4/76

Staphylococcus spp. human-derived MIC breakpoints

Amikacin

≤4

8

≥16

Staphylococcus spp. dog

Rifampicin

≤1

2

≥4

Staphylococcus spp. human-derived MIC breakpoints

Enrofloxacin

≤0.5

1–2

≥4

Staphylococcus spp. dog

Marbofloxacin

≤1

2

≥4

Staphylococcus spp. dog

Clindamycin

≤0.5

1–2

≥4

Staphylococcus spp. dog

Erythromycin

≤0.5

1–4

≥8

Staphylococcus spp. human-derived MIC breakpoints

Doxycycline

≤0.12

0.25

≥0.5

S. pseudintermedius dog

Chloramphenicol

≤8

16

≥32

Staphylococcus spp. human-derived MIC breakpoints

Gentamicin^a

≤4

8

≥16

human-derived MIC breakpoints

Ticarcillin^b

≤16

32–64

≥128

human-derived MIC breakpoints

Ticarcillin/Clavulanic acid^b

≤16/2

32/2–64/2

≥128/2

human-derived MIC breakpoints