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Table 2 Fold change of selected genes in liver tissue

From: Expression of selected genes isolated from whole blood, liver and obex in lambs with experimental classical scrapie and healthy controls, showing a systemic innate immune response at the clinical end-stage

Gene function

Gene Name

Fold change ± SEM

TNF super family

TNFa

Tumor Necrosis Factor alfa

−1.77 ± 0.12

Acute phase protein

SAA

Serum Amyloid A

89.98 ± 46.32

TF

Transferrin

−1.68 ± 0.10

Hp

Haptoglobin

542.96 ± 216.93

Cp

Ceruloplasmin

1.98 ± 0.46

AAT

Alpha-1 antitrypsin

−2.37 ± 0.05

TTR

Transthyretin

−2.03 ± 0.08

  1. Mean hepatic gene expression and SEM of the scrapie group at 23 wpi with fold change ≥1.5 relative to the mean expression in the control group scaled to 1
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BMC Veterinary Research

ISSN: 1746-6148

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