From: A randomized placebo-controlled trial of the efficacy and safety of a terbinafine, florfenicol and betamethasone topical ear formulation in dogs for the treatment of bacterial and/or fungal otitis externa
Adverse reactiona
Osurnia
Placebo
N
% of total (n = 190)
% of total (n = 158)
Elevated Alkaline Phosphatase
15
7.9
3
3.2
Vomiting
7
3.7
1
1.1
Elevated AST, ALT, ALPa
2
0
0.0
Weight Loss (10% BW)
0.53
Hearing Decrease/Loss