Table 5 Summary of body (kg) and organ (g) weights; mean (SD), N = 8 unless stated
Organ | Group 1 (sham) | Group 2 (2 mg/kg) | Group 3 (6 mg/kg) | Group 4 (10 mg/kg) | P-value1 Treatment |
|---|---|---|---|---|---|
Body weight | 11.23 (2.43) | 11.31 (2.28) | 11.18 (1.69) | 10.78 (1.68) | 0.8599 |
Adrenal glands | 1.05 (0.15) | 1.10 (0.21) | 1.09 (0.17) | 1.09 (0.16) | 0.9364 |
Brain | 75.69 (6.15) | 77.12 (4.93) | 78.50 (7.30) | 74.62 (4.03) | 0.4629 |
Epididymides (N = 4) | 3.70 (0.92) | 3.82 (0.42) | 4.35 (0.63) | 3.90 (0.30) | 0.4915 |
Heart | 86.57 (19.57) | 84.26 (13.63) | 85.48 (18.00) | 84.51 (17.31) | 0.9714 |
Kidneys | 54.25 (13.40) | 50.60 (8.81) | 49.37 (11.02) | 53.59 (14.19) | 0.5232 |
Liver | 316.83 (58.45) | 323.03 (37.76) | 303.03 (55.02) | 298.05 (60.58) | 0.6478 |
Lung | 90.49 (16.43) | 87.50 (12.44) | 87.09 (14.23) | 90.07 (13.05) | 0.7920 |
Ovaries (N = 4) | 1.86 (0.51) | 1.88 (0.22) | 1.29 (0.30) | 1.14 (0.41) | 0.0319 |
Pituitary glands | 0.07 (0.01) | 0.07 (0.02) | 0.07 (0.01) | 0.08 (0.02) | 0.3945 |
Salivary gland | 5.45 (1.43) | 5.36 (0.99) | 5.69 (1.08) | 5.14 (1.16) | 0.8261 |
Spleen | 50.93 (15.95) | 69.04 (15.92) | 52.13 (20.22) | 71.59 (20.26) | 0.0131 |
Testes (N = 4) | 13.35 (4.02) | 17.37 (3.19) | 16.36 (4.48) | 17.91 (2.86) | 0.3470 |
Thymus gland | 6.39 (3.49) | 7.47 (3.34) | 7.72 (3.62) | 5.43 (1.77) | 0.4936 |
Thyroid/parathyroid glands | 0.87 (0.20) | 0.88 (0.19) | 0.89 (0.18) | 1.00 (0.16) | 0.4457 |