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Table 4 Clinical signs (%) and pathological lesions (%) in pigs challenged with Pasteurella multocida type A

From: Pathogenic variability among Pasteurella multocida type A isolates from Brazilian pig farms

Variables Groups† p*
G0 G1 G2 G3 G4 G5 G6 G7 G8
Clinical signs
 Hyperthermia 0.00b 100.0a 62.50ab 100.0a 75.00ab 75.00ab 12.50b 100.0a 25.00b < 0.0001
 Dyspnea 0.00c 100.0a 37.50b 87.50ab 0.00bc 25.00bc 0.00bc 100.0a 0.00bc < 0.0001
 Cough 16.67b 50.00ab 37.50ab 12.50b 0.00b 37.50ab 0.00b 87.50a 0.00b 0.0002
Macroscopic lesions
 Cranioventral lung consolidation** 0.00c 62.50ab 37,5,00ab 87.50a 12.50b 0.00bc 0.00bc 75.00a 0.00bc < 0.0001
 Cranioventral lung consolidation (%)*** 0.00 ± 0.00b 3.58 ± 1.51ab 2.53 ± 1.43ab 6.26 ± 2.38a 1.30 ± 1.30b 0.00 ± 0.00b 0.00 ± 0.00b 5.01 ± 1.58a 0.000 ± 0.00b 0.0004
 Necrotic nodules 0.00c 62.50a 37.50ab 75.00a 0.00bc 0.00bc 0.00bc 37.50ab 0.00bc < 0.0001
 Diffuse fibrinous pleuritis 0.00c 50.00ab 0.00bc 75.00a 0.00bc 25.00abc 0.00bc 50.00ab 0.00bc < 0.0001
 Mild focal fibrinous pleuritis 0.00 0.00 0.00 0.00 0.00 12.50 0.00 12.50 0.00 0.7074
 Diffuse fibrinous pericarditis 0.00c 25.00abc 25.00abc 62.50a 0.00bc 25.00abc 0.00bc 37.50ab 0.00bc 0.0029
 Fibrinous peritonitis 0.00d 62.50a 12.50bcd 37.50ab 25.00abc 50.00ab 0.00cd 50.00ab 0.00cd < 0.0001
Microscopic lesions
 Fibrinonecrotic suppurative/fibrinonecro-haemorrhagic pleuropneumonia 0.00c 87.50a 50.00ab 87.50a 0.00bc 0.00bc 0.00bc 75.00a 0.00bc < 0.0001
 Fibrinopurulent pleuropneumonia 0.00 0.00 0.00 0.00 12.50 0.00 0.00 12.50 0.00 0.7074
 Suppurative lymphadenitis 0.00c 12.50bc 37.50ab 75.00a 12.50bc 12.50bc 0.00bc 37.50ab 0.00bc 0.0005
  1. Fever: Rectal temperature ≥ 40.0 °C
  2. *Descriptive level of probability by Fisher’s exact test; percentages followed by different letters on the same line differ significantly by Fisher’s exact test (p ≤ 0.05)
  3. **Suppurative bronchopneumonia in the histopathology assay
  4. ***Lung consolidation was measured based on the total percentage of the affected pulmonary area. Descriptive level of Kruskal-Wallis probability; averages followed by different letters differ significantly by the Wilcoxon test (p ≤ 0:05)
  5. †G0 with 12 pigs and G1-G8 with eight pigs per group