Fig. 3From: Immunohistochemical staining patterns of alpha-keratins in normal tissues from two reptile species: implications for characterization of squamous cell carcinomasSquamous cell carcinoma, skin, bearded dragon (Pogona vitticeps). a Immunohistochemistry for acidic alpha-keratin (AE1 positive) showing intense immunoreactivity in all layers of the nests of neoplastic cells, including the cornified layer of the keratin pearls. Bar = 100 μm. b Immunohistochemistry for basic alpha-keratin (AE3 positive) showing weak immunoreactivity in the basal and intermediate layers of the nests of neoplastic cells (arrows); no reactivity was observed in the cornified layer of the keratin pearls (*). Bar = 60 μm. Dako EnVision+ System, Harris haematoxylin counterstainBack to article page