Effect of prolonged submaximal exercise on serum oxidative stress biomarkers (d-ROMs, MDA, BAP) and oxidative stress index in endurance horses

Table 4 Values of serum OS biomarkers in horses pre- and post-races by separate race events

Parameter (unit)		First race		Second race		Third race		Fourth race
Parameter (unit)		40 km (n = 12)	80 km (n = 7)	40 km (n = 2)	80 km (n = 3)	40 km (n = 8)	80 km (n = 8)	40 km (n = 8)	80 km (n = 5)
d-ROMs (U.Carr.)	Pre-race	160.9 ± 11.8	172.7 ± 16.8	163.8 ± 13.5	184.9 ± 27.4	162.7 ± 9.2	163.3 ± 17.5	174.9 ± 6.2	157.2 ± 12.1
	Post-race	176.0 ± 13.2	175.6 ± 20.2	161.7 ± 0.7	184.2 ± 22.0	169.1 ± 8.9	173.8 ± 19.7	173.0 ± 8.2	156.7 ± 14.7
	P	< 0.001	0.7	0.9	0.9	0.06	0.07	0.7	0.9
	P^a	0.07		0.9		0.5		0.9
BAP (μmol/L)	Pre-race	2575.8 ± 51.6	2628.6 ± 71.9	2820.0 ± 40.0	2573.3 ± 53.6	2556.3 ± 52.6	2446.3 ± 21.5	2692.5 ± 34.3	2516.0 ± 53.5
	Post-race	2806.7 ± 49.0	2837.1 ± 90.3	2905.0 ± 155.0	2883.3 ± 69.4	2812.5 ± 33.6	2836.3 ± 32.3	2818.8 ± 29.3	2826.0 ± 65.7
	P	< 0.001	0.04	0.7	0.06	< 0.001	< 0.001	< 0.01	< 0.01
	P^a	0.8		0.3		0.03		0.02
MDA (μmol/L)	Pre-race	4.9 ± 0.2	4.5 ± 0.2	8.2 ± 1.9	3.8 ± 0.2	5.2 ± 0.2	4.6 ± 0.1	4.8 ± 0.1	4.3 ± 0.2
	Post-race	4.9 ± 0.2	4.9 ± 0.3	7.8 ± 0.7	3.5 ± 0.1	5.3 ± 0.2	4.8 ± 0.2	5.7 ± 0.4	5.2 ± 0.3
	P	0.8	0.2	0.8	0.08	0.5	0.5	0.08	0.02
	P^a	0.3		0.9		0.9		0.9
OSI (arbitraryunits)	Pre-race	6.2 ± 0.4	6.7 ± 0.8	5.8 ± 0.4	7.1 ± 0.9	6.4 ± 0.4	6.7 ± 0.7	6.5 ± 0.3	6.2 ± 0.4
	Post-race	6.2 ± 0.4	6.3 ± 0.9	5.6 ± 0.3	6.4 ± 0.7	6.0 ± 0.3	6.1 ± 0.6	6.1 ± 0.3	5.5 ± 0.5
	P	0.9	0.07	0.2	0.07	0.08	0.02	0.01	0.2
	P^a	0.05		0.1		0.4		0.4

d-ROMs determination of reactive oxidative metabolites, BAP biological antioxidant potential, MDA malondialdehyde, OSI oxidative stress index
P-significance for the differences within each category division (e.g. change in pre-race and post-race values)
P^a-significance for the difference between the two categories (e.g. change in values at 40 km vs. 80 km)

ISSN: 1746-6148