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Table 2 Groups division and results of antibodies, clinical signs in safety test

From: Safety and immunogenicity of an attenuated Chinese pseudorabies variant by dual deletion of TK&gE genes

Groups A(N) B(N) C(N) D(N) E(N)
 Inoculation route    I.N. I.M.  
 PRV strain tested    PRVΔTK&gE-AH02 LA-AB PRVΔTK&gE-AH02 LA-AB  
 ELISA antibodies against PRV gB or gE B.I. gB+ 0a/4b 0/4 0/4 0/4 0/4
14d P.I. gB+ 3/3 / 4/4 1/1 0/4
gE+ 0/3 / 0/4 0/1 0/4
 Morbidity   2/4 4/4 1/4 4/4 0/4
 Mortality   1/4 4/4 0/4 3/4 0/4
Groups A(P) B(P) C(P) D(P) E(P)
 Inoculation route    I.N. I.M.  
 PRV strain tested    PRVΔTK&gE-AH02 LA-AB PRVΔTK&gE-AH02 LA-AB  
 ELISA antibodies against PRV gB or gE B.I. gB+ 4/4 4/4 4/4 4/4 4/4
14d P.I. gB+ 4/4 4/4 4/4 4/4 4/4
gE+ 0/4 0/4 0/4 0/4 0/4
 Morbidity   0/4 0/4 0/4 0/4 0/4
 Mortality   0/4 0/4 0/4 0/4 0/4
  1. I.N. means intranasally, I.M. means intramuscularly, gB+ means antibodies against PRV gB positive, gE+ means antibodies against PRV gE positive, B.I. means before inoculation, P.I. means post inoculation. “a” indicates the number of piglets positive;“b” indicates the number of piglets in the group