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Table 2 Groups division and results of antibodies, clinical signs in safety test

From: Safety and immunogenicity of an attenuated Chinese pseudorabies variant by dual deletion of TK&gE genes

Groups

A(N)

B(N)

C(N)

D(N)

E(N)

 Inoculation route

  

I.N.

I.M.

 

 PRV strain tested

  

PRVΔTK&gE-AH02

LA-AB

PRVΔTK&gE-AH02

LA-AB

 

 ELISA antibodies against PRV gB or gE

B.I.

gB+

0a/4b

0/4

0/4

0/4

0/4

14d P.I.

gB+

3/3

/

4/4

1/1

0/4

gE+

0/3

/

0/4

0/1

0/4

 Morbidity

 

2/4

4/4

1/4

4/4

0/4

 Mortality

 

1/4

4/4

0/4

3/4

0/4

Groups

A(P)

B(P)

C(P)

D(P)

E(P)

 Inoculation route

  

I.N.

I.M.

 

 PRV strain tested

  

PRVΔTK&gE-AH02

LA-AB

PRVΔTK&gE-AH02

LA-AB

 

 ELISA antibodies against PRV gB or gE

B.I.

gB+

4/4

4/4

4/4

4/4

4/4

14d P.I.

gB+

4/4

4/4

4/4

4/4

4/4

gE+

0/4

0/4

0/4

0/4

0/4

 Morbidity

 

0/4

0/4

0/4

0/4

0/4

 Mortality

 

0/4

0/4

0/4

0/4

0/4

  1. I.N. means intranasally, I.M. means intramuscularly, gB+ means antibodies against PRV gB positive, gE+ means antibodies against PRV gE positive, B.I. means before inoculation, P.I. means post inoculation. “a” indicates the number of piglets positive;“b” indicates the number of piglets in the group