Safety and immunogenicity of an attenuated Chinese pseudorabies variant by dual deletion of TK&gE genes

BMC Veterinary Research

Table 2 Groups division and results of antibodies, clinical signs in safety test

Groups			A(N)	B(N)	C(N)	D(N)	E(N)
Inoculation route			I.N.		I.M.
PRV strain tested			PRV^ΔTK&gE-AH02	LA-A^B	PRV^ΔTK&gE-AH02	LA-A^B
ELISA antibodies against PRV gB or gE	B.I.	gB+	0^a/4^b	0/4	0/4	0/4	0/4
	14d P.I.	gB+	3/3	/	4/4	1/1	0/4
	14d P.I.	gE+	0/3	/	0/4	0/1	0/4
Morbidity			2/4	4/4	1/4	4/4	0/4
Mortality			1/4	4/4	0/4	3/4	0/4
Groups			A(P)	B(P)	C(P)	D(P)	E(P)
Inoculation route			I.N.		I.M.
PRV strain tested			PRV^ΔTK&gE-AH02	LA-A^B	PRV^ΔTK&gE-AH02	LA-A^B
ELISA antibodies against PRV gB or gE	B.I.	gB+	4/4	4/4	4/4	4/4	4/4
	14d P.I.	gB+	4/4	4/4	4/4	4/4	4/4
	14d P.I.	gE+	0/4	0/4	0/4	0/4	0/4
Morbidity			0/4	0/4	0/4	0/4	0/4
Mortality			0/4	0/4	0/4	0/4	0/4

I.N. means intranasally, I.M. means intramuscularly, gB+ means antibodies against PRV gB positive, gE+ means antibodies against PRV gE positive, B.I. means before inoculation, P.I. means post inoculation. “^a” indicates the number of piglets positive;“^b” indicates the number of piglets in the group

ISSN: 1746-6148