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Table 1 Pharmacokinetics parameters

From: Pharmacokinetics of rectal levetiracetam as add-on treatment in dogs affected by cluster seizures or status epilepticus

 

Cmax

(μg/ml)

Tmax

(min)

AUC0-t

(μg-h/ml)

t ½

(min)

“Non-responders”

(n = 2)

12.7 and 17.53

90 and 30

89.63 and 105.24

153 and 249

“Responders”

(n = 6)

43.02 ± 7.27

100.2 ± 64.8

337.94 ± 83.41

268.6 ± 75.8

  1. No adverse effects specifically attributable to LEV administration were noted at any time point