From: Pharmacokinetics of rectal levetiracetam as add-on treatment in dogs affected by cluster seizures or status epilepticus
Cmax
(μg/ml)
Tmax
(min)
AUC0-t
(μg-h/ml)
t ½
“Non-responders”
(n = 2)
12.7 and 17.53
90 and 30
89.63 and 105.24
153 and 249
“Responders”
(n = 6)
43.02 ± 7.27
100.2 ± 64.8
337.94 ± 83.41
268.6 ± 75.8