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Table 2 Viremia of immunized goats following BVDV challenge using RT-qPCR

From: Recombinant E2 protein enhances protective efficacy of inactivated bovine viral diarrhea virus 2 vaccine in a goat model

Goat No. aDays post-challenge
  1 3 5 7 8 9 10 11 12 13 14 15 17 19 21
iBVDV+rE2
 241
 250
 546
rE2
 541
 542 + + + + +b +
 543
iBVDV
 37 +
 244 +
 246
Saline
 538 + + + + + +
 539 + + + + + + +
 533 + + + + + + +
  1. aGoats were immunized twice intramuscularly with four different vaccine formulations: 1) inactivated BVDV+rE2, 2) rE2, 3) inactivated BVDV, and 4) saline, and challenged with 1 × 108 FAID50 BVDV/TW 2014 4 weeks after primary immunization. Viremia was detected using RT-qPCR for 21 days after challenge for each animal. Samples that reacted with the RT-qPCR were designated positive (+) and non-reactive samples were designated negative (−)
  2. bUsing the Pearson chi-square test, for viremia between 7 and 13 days post challenge, the p value was 0.017 when comparing between iBVDV+rE2 and rE2, and 0.147 when comparing between iBVDV+rE2 and iBVDV