Skip to main content

Table 3 Analysis of amino acid types in QRDRs and ARGs in S. sonnei isolates with resistance to fluoroquinolones and/or cephalosporin

From: Molecular characterization of fluoroquinolone and/or cephalosporin resistance in Shigella sonnei isolates from yaks

Strain name Antimicrobial resistance profiles Fluoroquinolone resistance genes Cephalosporin resistance genes
QRDR PMQR genes TEM OXA CTX-M
gyrA parC aac(6′)-Ib-cr qnr
83 (S) 87 (D) 80 (S)
SS036 ENR/TE L D S aac(6′)-Ib-cr NA --- --- ---
SS019 ENR/AMP/TE/CN L D S aac(6′)-Ib-cr NA --- --- ---
SS002 NOR/ENR/AMP/TE L D S aac(6′)-Ib-cr NA --- --- ---
SS008 NOR/ENR/AMP/TE/S L N S aac(6′)-Ib-cr qnrB --- --- ---
SS043 NOR/ENR/AMP/TE/S L D I aac(6′)-Ib-cr NA --- --- ---
SS029 NOR/ENR/AMP/C/TE/S/CN L N S aac(6′)-Ib-cr NA --- --- ---
SS018 AMP/KZ/TE/S --- --- --- --- --- TEM-1 NA NA
SS024 AMP/KF/KZ/TE --- --- --- --- --- TEM-1 NA NA
SS035 AMP/KF/KZ/TE --- --- --- --- --- TEM-1 NA NA
SS011 AMP/KF/KZ/TE/CN --- --- --- --- --- TEM-1 NA NA
SS031 AMP/KF/KZ/CRO/TE/S/CN --- --- --- --- --- TEM-1 OXA-1 NA
SS032 AMP/KF/KZ/CRO/TE/S/CN --- --- --- --- --- TEM-1 OXA-1 NA
SS006 AMP/KF/KZ/FOX/CRO/C/TE/S/CN --- --- --- --- --- TEM-1 OXA-1 NA
SS027 AMP/KF/KZ/FOX/CRO/CTX/TE/S/CN --- --- --- --- --- TEM-1 NA CTX-M-79
SS004 NOR/ENR/AMP/KF/KZ/TE/S/CN L N S aac(6′)-Ib-cr NA TEM-1 OXA-1 NA
SS028 NOR/ENR/LEV/AMP/KF/KZ/CRO/TE/S/CN L N I aac(6′)-Ib-cr NA TEM-1 OXA-1 NA
SS013 NOR/ENR/LEV/AMP/KF/KZ/CRO/CTX/TE/S L N I aac(6′)-Ib-cr NA TEM-1 OXA-1 CTX-M-14
SS039 NOR/ENR/LEV/AMP/KF/KZ/CRO/CTX/TE/S L N I aac(6′)-Ib-cr NA TEM-1 OXA-1 CTX-M-14
SS021 NOR/ENR/AMP/KF/KZ/FOX/CRO/CTX/C/TE/CN L N S aac(6′)-Ib-cr qnrS TEM-1 OXA-1 CTX-M-14
SS041 NOR/ENR/LEV/AMP/KF/KZ/FOX/CRO/CTX/TE/S/CN L N I aac(6′)-Ib-cr qnrS TEM-1 OXA-1 CTX-M-14
  1. S Ser, L Leu, D Asp, N Asn, I Ile, NA not available; “---”: not detected