Fig. 4
Nasal swab shedding of guinea pigs infected with the four virus strains in both the inoculation and contact groups. Guinea pigs were inoculated with the JS/10, KR/07, MV/12 and CA/09 virus strains. After 24 h on 1 dpi, additional naive guinea pigs were placed into each virus group as the contact group. Nasal swabs were collected every day for determination of the viral loads using real-time PCR and the results are expressed as log10 (viral RNA copies)/g. The solid line represents for the viral inoculation group (-I) and the dotted line represents for the virus contact group (-C) of four viruses. Each error bar indicates the standard deviation. *, P < 0.05, or **, P < 0.01, indicates significantly different virus titers in nasal swabs compared between group JS/10 and KR/07. * in black, represents significant difference in inoculation group, while * in red demonstrates significant difference in contact group. #, P < 0.05, or ##, P < 0.01, indicates a significant difference in virus titers for group MV/12 compared with group KR/07. # in black, represents significant difference in inoculation group, while # in red demonstrates significant difference in contact group. All significant differences are shown above the figure