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Table 4 Number and percentages of CTL clones from BH053 and BH051 recognizing multiple T. parva strains

From: Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animals

Calf

BG053 (M)

BG051 (C)

Total

18

38

1 strain

1 (6)

29 (76)

2 strains

5 (28)

2 (5)

3 strains

5 (28)

2 (5)

4 strains

7 (39)

4 (11)

5 strains

0 (0)

1 (3)

Muguga (4230)

ND

2 (5)

Serengeti (4229)

ND

6 (16)

Kiambu-5 (4228)

ND

33 (87)

Muguga (3308)

18 (100)

2 (5)

Uganda (3645)

16 (89)

7 (18)

Mariakani (3212)

9 (50)

5 (13)

Boleni (3230)

8 (44)

1 (3)

Marikebuni (3292)

3 (17)

6 (16)

  1. Upper part of the table: The total number of clones with percentages in brackets, that recognize multiple cloned T. parva strains, with a cutoff value of 5% cytotoxicity, for the haplotype matched pair, BG053 (Muguga immunized) and BG051 (Muguga cocktail immunized), is shown. Each clone was analyzed for the number of strains that it recognized. The left numbers in each column represents the actual number of clones recognizing 1 strain, 2 strains, etc. The numbers in brackets represents the corresponding percentages of clones recognizing 1 strain, 2 strains etc. Percentages have been rounded. Lower part of the table: The total number of clones and percentages in brackets from BG053 and BG051 recognizing the different T. parva strains. Percentages have been rounded. BH051 was tested on the Muguga cocktail component reference stabilate strains in addition to the cloned strains. (ND) Not determined