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Table 2 Cytotoxic T cell responses in immunized cattle assayed on target cells infected with different cloned T. parva strains

From: Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animals

Muguga

Uganda

3308

Mariakani

3645

Boleni

3212

Marikebuni

3230

Control

3292

 

BG033 (M)

34

13

35

16

ND

0

BG042 (C)

26

18

17

9

18

0

BG053 (M)

59

40

14

20

34

0

BG051 (C)

51

25

38

22

28

3

BG052 (M)

38

33

25

23

17

4

BG056 (C)

3

22

20

11

13

3

BH055 (M)

40

30

26

13

20

0a

BH047 (C)

10

8

8

7

4

0

  1. Cytotoxic T cell responses using autologous PBMC infected with different cloned T. parva strains as target cells. The specific cytotoxicity at effector/target ratios of 10:1 are shown. Each value is deduced from an effector (CTL) titration curve as shown in Fig. 1. (M) Muguga 3308 immunized; (C) Muguga cocktail immunized. (ND) Not determined, (a) Control was autologous PBMC. Relative differences of the CTL specificities, between M and C, were tested using ANOVA analysis (P = 0.421)