Fig. 2From: Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animalsCytotoxicity obtained by T cell clones on a panel of target cells infected with different cloned T. parva strains. The cutoff value was 5% cytotoxicity. Clones were categorized into clonotypes based on their pattern of reactivity. The level of cytotoxicity is visualized as a heat map – colour codes are shown. a Calf BG053 immunized with Muguga 3308. CD8 T cell clones were generated from CD8-purified bulk cultures and tested for cytotoxicity to 5 different strains (as shown) and a MHC-mismatched control TpM. b The haplotype-matched calf BG051 immunized with the Muguga cocktail 0801. Clones were tested for cytotoxicity on the same target cells as BG053 and the additional components of the Muguga CocktailBack to article page