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Fig. 2 | BMC Veterinary Research

Fig. 2

From: Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animals

Fig. 2

Cytotoxicity obtained by T cell clones on a panel of target cells infected with different cloned T. parva strains. The cutoff value was 5% cytotoxicity. Clones were categorized into clonotypes based on their pattern of reactivity. The level of cytotoxicity is visualized as a heat map – colour codes are shown. a Calf BG053 immunized with Muguga 3308. CD8 T cell clones were generated from CD8-purified bulk cultures and tested for cytotoxicity to 5 different strains (as shown) and a MHC-mismatched control TpM. b The haplotype-matched calf BG051 immunized with the Muguga cocktail 0801. Clones were tested for cytotoxicity on the same target cells as BG053 and the additional components of the Muguga Cocktail

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