Fig. 11

Histopathology of facial canine discoid lupus erythematosus. a: in a biopsy from the nasal planum, cell-rich, lymphocytic interface dermatitis is present with a prominent band-like (lichenoid) dermal infiltrate of lymphocytes and plasma cells. Pigmentary incontinence is moderate. 100× (b): inset box from image “a”, a short epidermal segment with well-developed interface change, where lymphocytes infiltrate predominantly the basal layer in conjunction with basal cell vacuolation, apoptosis, and loss. 400X (c): a similar interface reaction pattern affects the epidermis of haired skin in the dorsal nasal area. 200X (d): lymphocytic interface folliculitis and mural folliculitis of the hair follicle infundibulum. 200X