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Table 7 Lesion score (Mean ± SE) for histopathological changes in kidneys during sub-chronic L. camara toxicity in guinea pigs

From: Sub-chronic toxicopathological study of lantadenes of Lantana camara weed in Guinea pigs

Group Necrosis Fibrosis Degenerative change Inflammatory change Hyaline casts formation Epithelial casts formation Apoptosis
GI 2.33 ± 0.21c 2.00 ± 0.26c 2.50 ± 0.22c 2.17 ± 0.31b 2.83 ± 0.17c 2.67 ± 0.21c 1.67 ± 0.21b
GII 2.00 ± 0.26bc 1.50 ± 0.22bc 2.50 ± 0.22c 1.83 ± 0.31b 2.50 ± 0.22bc 2.33 ± 0.21bc 1.00 ± 0.37ab
GIII 1.17 ± 0.31abc 0.83 ± 0.17abc 1.33 ± 0.21abc 1.17 ± 0.31ab 1.50 ± 0.34abc 1.17 ± 0.31abc 0.83 ± 0.17ab
G1V 0.67 ± 0.21ab 0.33 ± 0.21ab 0.67 ± 0.21ab 0.83 ± 0.31ab 0.50 ± 0.22ab 0.50 ± 0.22ab 1.00 ± 0.26ab
GV 0.00 ± 0.00a 0.00 ± 0.00a 0.00 ± 0.00a 0.00 ± 0.00a 0.00 ± 0.00a 0.00 ± 0.00a 0.00 ± 0.00a
  1. a-cValues within columns with different superscripts differ significantly by ANOVA (P ≤ 0.05). GI = Lantadenes @ 24 mg/kg bw; GII = Lantadenes @ 18 mg/kg bw; GIII = Lantadenes @ 12 mg/kg bw; GIV = Lantadenes @ 6 mg/kg bw; GV = control group, n = 6