Sub-chronic toxicopathological study of lantadenes of Lantana camara weed in Guinea pigs

BMC Veterinary Research

Table 5 Lipid peroxidation, catalase, superoxide dismutase, reduced glutathione, and protein values (Mean ± SE) in tissue homogenate of kidneys during sub-chronic L. camara toxicity in guinea pigs

Group	LPO (μM of MDA/g wet tissue)	Catalase (K/mg protein)	Superoxide dismutase (U /mg protein)	Reduced glutathione (nM/ g of wet tissue)	Protein (mg/dl)
GI	1.78 ± 0.34^a	12.83 ± 0.46^a	3.94 ± 0.16^a	20.12 ± 1.92^a	68.46 ± 4.54^a
GII	1.24 ± 0.20^ab	15.22 ± 1.14^ab	4.46 ± 0.31^a	25.54 ± 1.78^ab	74.64 ± 7.42^a
GIII	0.92 ± 0.21^b	15.78 ± 1.48^ab	5.23 ± 0.50^ab	25.71 ± 1.66^ab	95.66 ± 16.52^ab
GIV	0.68 ± 0.13^b	18.52 ± 2.64^ab	5.19 ± 0.33^ab	30.57 ± 2.04^b	116.92 ± 11.3^b
GV	0.64 ± 0.09^b	20.31 ± 2.21^b	6.76 ± 0.66^b	31.45 ± 0.98^b	118.19 ± 12.65^b

^a-bValues within columns with different superscripts differ significantly by ANOVA (P ≤ 0.05). GI = Lantadenes @ 24 mg/kg bw; GII = Lantadenes @ 18 mg/kg bw; GIII = Lantadenes @ 12 mg/kg bw; GIV = Lantadenes @ 6 mg/kg bw; GV = control group, n = 6

ISSN: 1746-6148