TY - JOUR AU - Váradyová, Zora AU - Mravčáková, Dominika AU - Babják, Michal AU - Bryszak, Magdalena AU - Grešáková, Ľubomíra AU - Čobanová, Klaudia AU - Kišidayová, Svetlana AU - Plachá, Iveta AU - Königová, Alžbeta AU - Cieslak, Adam AU - Slusarczyk, Sylwester AU - Pecio, Lukasz AU - Kowalczyk, Mariusz AU - Várady, Marián PY - 2018 DA - 2018/03/09 TI - Effects of herbal nutraceuticals and/or zinc against Haemonchus contortus in lambs experimentally infected JO - BMC Veterinary Research SP - 78 VL - 14 IS - 1 AB - The gastrointestinal parasitic nematode Haemonchus contortus is a pathogenic organism resistant to several anthelmintics. This study assessed the efficacy of a medicinal herbal mixture (Herbmix) and organic zinc, as an essential trace element for the proper functioning of both unspecific and specific immune defensive mechanisms, against experimental infections with H. contortus in lambs. All lambs were infected orally with approximately 5000 third-stage larvae of a strain of H. contortus susceptible to anthelmintics (MHco1). Twenty-four female lambs 3–4 months of age were divided into four groups: unsupplemented animals (control), animals supplemented with Herbmix (Hmix), animals supplemented with organic zinc (Zn) and animals supplemented with Herbmix and organic zinc (Hmix+Zn). Eggs per gram (EPG) of faeces were quantified 20, 28, 35, 42, 49, 56, 62 and 70 d post-infection and mean abomasal worm counts were assessed 70 d post-infection. Samples of blood were collected from each animal 7, 35, 49 and 70 d post-infection. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-018-1405-4 DO - 10.1186/s12917-018-1405-4 ID - Váradyová2018 ER -