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Table 1 Animal information and results for study elk

From: Pathologic and biochemical characterization of PrPSc from elk with PRNP polymorphisms at codon 132 after experimental infection with the chronic wasting disease agent

Animal number

1

2

3

4

5

6

7

8

 Genotype codon 132

MM

MM

LM

LM

LL

LL

LL

LL

 Incubation period (MPI)

23

23

38

40

60

63

64

64

 Clinical presentation

LBC, Rec

LBC, Rec

LBC, ataxia

LBC

LBC

Neuro

FD

LBC

Tissue results

 Brain

+/+

+/+

+/+

+/+

+/+

+/+

+/+

+/+

 Retina

+

+

+

+

+

+

+

+

 Peripheral NS

+

+

+

–

+

+

–

+

 Lymphoid head

+

+

+

+

+

+

+

+

 Lymphoid other

+

+

+

+

+

+

+

n/a

 Intestines

+

+

+

+

–

+

+

+

 Spleen

+

+

+

–

+

–

–

+

 Pituitary

n/a

n/a

+

+

n/a

+

–

n/a

 Foregut

n/a

–

–

+

–

–

–

+

 Adrenal

n/a

+

–

–

n/a

–

+

n/a

  1. M methionine, L leucine, MPI months post inoculation, LBC Loss of body condition, Rec recumbency, Neuro neurological signs (for more detail see Results), FD found dead. Tissue results: brain, vacuolation/PrPSc; other tissues, PrPSc; n/a, tissue not available for examination