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Table 4 Mean ± SD of Ins concentrations (mmol/L of brain water) and Ins/tCr ratios

From: Effects of isoflurane, sevoflurane, propofol and alfaxalone on brain metabolism in dogs assessed by proton magnetic resonance spectroscopy (1H MRS)

  Dose 1 Dose 2 Dose 3 Arithmetic mean
Mean ± SD Mean ± SD Mean ± SD Mean ± SD
Ins BG Isoflurane 7.931 ± 0.343 7.983 ± 0.589 7.730 ± 0.824 7.876 ± 0.529
Sevoflurane 8.365 ± 0.816 8.470 ± 0.780 8.344 ± 0.710 8.393 ± 0.701
Propofol 8.033 ± 0.561 8.056 ± 0.778 8.109 ± 0.646 8.100 ± 0.601
Alfaxalone 8.325 ± 0.606 8.446 ± 0.689 8.605 ± 0.487 8.459 ± 0.470
PL Isoflurane 7.679 ± 0.996 8.176 ± 0.861 8.070 ± 0.716 8.016 ± 0.835
Sevoflurane 8.165 ± 0.445 8.367 ± 0.528 8.131 ± 0.485 8.221 ± 0.414
Propofol 8.178 ± 1.075 7.976 ± 1.266 7.833 ± 1.439 7.992 ± 1.196
Alfaxalone 7.967 ± 1.103 8.177 ± 1.078 8.188 ± 0.888 8.111 ± 0.954
OL Isoflurane 8.005 ± 0.885 8.233 ± 0.871 8.077 ± 1.171 8.016 ± 1.087
Sevoflurane 8.362 ± 0.620 8.588 ± 0.554 8.342 ± 0.677 8.431 ± 0.579
Propofol 8.382 ± 0.611 8.455 ± 0.749 8.336 ± 0.593 8.501 ± 0.752
Alfaxalone 8.524 ± 0.649 8.449 ± 0.629 8.523 ± 0.572 8.499 ± 0.591
Ins/tCr BG Isoflurane 1.365 ± 0.114 1.299 ± 0.082 1.331 ± 0.100 1.326 ± 0.075
Sevoflurane 1.389 ± 0.132 1.333 ± 0.137 1.336 ± 0.095 1.353 ± 0.103
Propofol 1.351 ± 0.124 1.335 ± 0.112 1.353 ± 0.114 1.307 ± 0.167
Alfaxalone 1.319 ± 0.108 1.334 ± 0.099 1.340 ± 0.110 1.331 ± 0.081
PL Isoflurane 1.417 ± 0.173 1.462 ± 0.145 1.439 ± 0.112 1.443 ± 0.136
Sevoflurane 1.510 ± 0.135 1.502 ± 0.084 1.457 ± 0.121 1.490 ± 0.107
Propofol 1.459 ± 0.221 1.451 ± 0.266 1.431 ± 0.271 1.440 ± 0.242
Alfaxalone 1.462 ± 0.214 1.509 ± 0.215 1.525 ± 0.211 1.498 ± 0.200
OL Isoflurane 1.203 ± 0.081 1.205 ± 0.092 1.245 ± 0.113 1.220 ± 0.103
Sevoflurane 1.242 ± 0.090 1.258 ± 0.077 1.228 ± 0.115 1.243 ± 0.089
Propofol 1.235 ± 0.056 1.287 ± 0.197 1.120 ± 0.326 1.256 ± 0.232
Alfaxalone 1.262 ± 0.098 1.259 ± 0.100 1.304 ± 0.160 1.275 ± 0.113
  1. Mean ± SD for the three different doses and the arithmetic mean of the three doses for isoflurane, sevoflurane, propofol and alfaxalone in basal ganglia (BG), parietal lobe (PL) and occipital lobe (OL).