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Table 3 Mean ± SD of tCh concentrations (mmol L-1 of brain water) and tCh/tCr ratios

From: Effects of isoflurane, sevoflurane, propofol and alfaxalone on brain metabolism in dogs assessed by proton magnetic resonance spectroscopy (1H MRS)

  Dose 1 Dose 2 Dose 3 Arithmetic mean
Mean ± SD Mean ± SD Mean ± SD Mean ± SD
tCh BG Isoflurane 1.887 ± 0.112A 2.079 ± 0.110 1.932 ± 0.166A 1.969 ± 0.0891
Sevoflurane 1.971 ± 0.109A 2.107 ± 0.145B 2.068 ± 0.128AB 2.049 ± 0.10312
Propofol 2.034 ± 0.118 2.015 ± 0.109 2.010 ± 0.139 2.026 ± 0.09012
Alfaxalone 2.069 ± 0.103 2.082 ± 0.105 2.108 ± 0.123 2.086 ± 0.0802
PL Isoflurane 1.805 ± 0.180A 1.885 ± 0.129B 1.841 ± 0.132AB 1.843 ± 0.134
Sevoflurane 1.721 ± 0.107A 1.806 ± 0.100B 1.747 ± 0.133AB 1.758 ± 0.101
Propofol 1.843 ± 0.117 1.773 ± 0.233 1.788 ± 0.204 1.768 ± 0.218
Alfaxalone 1.854 ± 0.103 1.822 ± 0.107 1.814 ± 0.162 1.830 ± 0.112
OL Isoflurane 1.616 ± 0.288 1.805 ± 0.121 1.667 ± 0.202 1.653 ± 0.2581
Sevoflurane 1.707 ± 0.148A 1.807 ± 0.094B 1.768 ± 0.132AB 1.761 ± 0.11812
Propofol 1.795 ± 0.122 1.831 ± 0.122 1.832 ± 0.116 1.823 ± 0.1052
Alfaxalone 1.812 ± 0.140 1.802 ± 0.102 1.789 ± 0.092 1.801 ± 0.09712
tCh/tCr BG Isoflurane 0.324 ± 0.021 0.339 ± 0.017 0.331 ± 0.043 0.330 ± 0.027
Sevoflurane 0.329 ± 0.033 0.332 ± 0.031 0.331 ± 0.020 0.330 ± 0.025
Propofol 0.342 ± 0.017 0.335 ± 0.025 0.335 ± 0.024 0.337 ± 0.020
Alfaxalone 0.328 ± 0.020 0.331 ± 0.018 0.328 ± 0.017 0.329 ± 0.016
PL Isoflurane 0.334 ± 0.039 0.338 ± 0.030 0.329 ± 0.029 0.332 ± 0.030
Sevoflurane 0.318 ± 0.033 0.324 ± 0.021 0.313 ± 0.023 0.319 ± 0.022
Propofol 0.329 ± 0.031 0.322 ± 0.047 0.325 ± 0.028 0.318 ± 0.043
Alfaxalone 0.342 ± 0.032 0.337 ± 0.027 0.338 ± 0.040 0.339 ± 0.030
OL Isoflurane 0.242 ± 0.031A 0.265 ± 0.010B 0.257 ± 0.008AB 0.251 ± 0.026
Sevoflurane 0.253 ± 0.020 0.265 ± 0.015 0.260 ± 0.023 0.260 ± 0.018
Propofol 0.265 ± 0.014 0.278 ± 0.028 0.268 ± 0.023 0.275 ± 0.027
Alfaxalone 0.268 ± 0.018 0.268 ± 0.016 0.273 ± 0.019 0.270 ± 0.015
  1. Mean ± SD for the three different doses and the arithmetic mean of the three doses for isoflurane, sevoflurane, propofol and alfaxalone in basal ganglia (BG), parietal lobe (PL) and occipital lobe (OL). Different alphabetical superscripts differ significantly (p < 0.05) between different doses of each anesthetic different numerical superscripts differ significantly between arithmetic mean tCh concentrations of each anesthetic